Cancer cells with a mutated SETD2 gene were killed by a drug called AZD1775 that inhibits a protein called WEE1 in a recent study. It is well known that mutations drive cancer cell growth and resistance to treatment. However, these mutations can also become a weak point for a tumor. The research team found that that was the case for cancer cells with mutations in a key cancer gene called SETD2.
New treatment targets cancers with particular genetic signature
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