The effectiveness of tried and tested medicines for the treatment of some of the heaviest burdens of our modern society including diseases such as cancer, diabetes and cardiovascular diseases. One molecule that these disorders have in common is a receptor known as the calcium-sensing receptor (CaSR), which is the molecular starting point of this project. Abnormal CaSR function can not only trigger familial benign hypercalcaemia and hyperparathyroidism but it is also involved in various other diseases such as Alzheimer's disease, diabetes, cancer and cardiovascular diseases. A four-year EU project is now investigating whether these medicines that modulate the function of CaSR, could be used for the treatment of the above-mentioned diseases.
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